MassIVE MSV000086844

Complete Public PXD024262

Resource allocation in the archaeon Methanococcus maripaludis during slow growth

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Description

We conducted a systems-level study on the physiology of slow growth in the archaeon Methanococcus maripaludis revealing a strategy for acclimation to slow growth that relies on redistribution of energy for cellular maintenance and changes in catabolic and ribosomal activity rather than gene regulation, a strategy that is distinct from well-known heterotrophic model bacteria such as E. coli. This dataset describes the proteome response of Methanococcus maripaludis to a formate (energy) limitation when grown in a chemostat at different growth rates. Samples contain both 14N and 15N-labeled peptides, with the 15N reference generated as a combination of batch exponential culture and a stationary phase cultures. [doi:10.25345/C51N58] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: archaea ; formate ; methanococcus maripaludis ; methanogen ; N15

Contact

Principal Investigators:
(in alphabetical order) 		Alfred M. Spormann, Stanford University, United States
James R. Williamson, The Scripps Research Institute, United States
Submitting User: patsalo

Publications

Müller AL, Gu W, Patsalo V, Deutzmann JS, Williamson JR, Spormann AM.
An alternative resource allocation strategy in the chemolithoautotrophic archaeon Methanococcus maripaludis.
Proc Natl Acad Sci U S A.

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