MassIVE MSV000094607

Partial Public PXD051702

Proteomic insights into the impact of COVID-19 on peripheral blood mononuclear cells in kidney transplant recipients

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Description

Background The emergence of the Coronavirus disease 2019 (COVID-19) pandemic in 2020 has profoundly impacted global health systems, particularly affecting vulnerable populations like kidney transplant recipients (KTRs). Methods We prospectively collected blood samples from 17 PCR-confirmed COVID-19 KTR patients and 10 non-COVID-19 KTRs between May and September 2020. Using tandem mass tag based quantitative proteomics, we characterized peripheral blood mononuclear cells (PBMCs) from KTRs alongside plasma protein biomarkers and lymphocyte counts, followed by bioinformatics analyses. [doi:10.25345/C50000B3F] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: COVID-19 ; kidney transplant recipient ; KTRs ; peripheral blood mononuclear cell ; PBMC

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Principal Investigators:
(in alphabetical order) 		Giuseppe Leite, Escola Paulista de Medicina/UNIFESP, Brazil
Reinaldo Salomao, Escola Paulista de Medicina/UNIFESP, Brazil
Submitting User: ggfleite
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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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