MassIVE MSV000097305

Partial Public PXD061774

A549 tumorigenic and BEAS-2B non-tumorigenic cell line derived small extracellular vesicles show distinct proteomic, N-glycoproteomic and chondroitin/dermatan sulfate profiles

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Description

In this study, we analyzed the proteomic, N-glycoproteomic, and chondroitin/dermatan sulfate glycosaminoglycan profiles of small extracellular vesicles derived from A549 lung adenocarcinoma and BEAS-2B non-tumorigenic epithelial cell lines. The media samples were used as a background. [doi:10.25345/C51834F3N] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: lung cancer ; extracellular vesicle ; proteomics ; N-glycoproteomics ; mass spectrometry ; DatasetType:Proteomics

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Principal Investigators:
(in alphabetical order) 		Lilla Turiak, HUN-REN Research Centre for Natural Sciences, Hungary
Submitting User: balbisimirjam
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Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
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