A total of 45 urine samples from 5 prostate cancer (PC) patients, 10 renal transplant patients with proven acute rejection (AR), 10 renal transplant patients with stable graft (STA), 10 non-specific proteinuria patients (NS), and 10 healthy individuals (HI), were utilized for global urine proteome profiling using 2D-LC-MS/MS. Peptides were digested with trypsin then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS Processing pipeline.
[doi:10.25345/C5M775]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: proteomics ; urine proteome ; human urine
Principal Investigators: (in alphabetical order) |
Wei-Jun Qian, Pacific Northwest National Laboratory, United States |
Submitting User: | alchemistmatt |
Swensen AC, He J, Fang AC, Ye Y, Nicora CD, Shi T, Liu AY, Sigdel TK, Sarwal MM, Qian WJ.
A Comprehensive Urine Proteome Database Generated From Patients With Various Renal Conditions and Prostate Cancer.
Front Med (Lausanne). Epub 2021 Apr 13.
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