MassIVE MSV000093769

Partial Public PXD048259

Alterations in the secretome composition arising from YIPF5 depletion or mutation

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Description

Secretome analysis was conducted on MCF10A cells with various conditions, including wild-type (wt) cells, YIPF5-depleted cells, cells with mutated YIPF5, and cells with re-expression of wild-type YIPF5. The primary objective was to discern alterations in the secretome composition arising from YIPF5 depletion or mutation. This investigation aimed to shed light on the influence of YIPF5 on the secretory profile of MCF10A cells, providing insights into potential changes in extracellular signaling and cellular communication associated with YIPF5 status. [doi:10.25345/C5416T948] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: secretory pathway ; secretome ; transport

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Principal Investigators:
(in alphabetical order) 		Christoph Kaether, Leibniz Institute on Aging, Fritz Lipmann Institute (FLI), Germany
Submitting User: ProteomicsCF_FLI
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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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This dataset may not contain all raw spectra data as originally deposited in PRIDE. It has been imported to MassIVE for reanalysis purposes, so its spectra data here may consist solely of processed peak lists suitable for reanalysis with most software.