MassIVE MSV000083145

Partial Public PXD011747

Integrated proteomic/lipidomics reveal that the swarming motility of Paenibacillus polymyxa is driven by phospholipid changes, surfactants, and flagellar specialization

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Description

To better understand the molecular-level details of the swarming phenotype in P. polymyxa,m this study was designed to use a bioinformatics approach to integrate proteomics and lipidomics datasets generated for P. polymyxa grown in liquid swimming culture bacteria vs. swarming on agar platesbacteria. Integration of omics datasets unraveled the growth condition dependent phospholipid metabolism and possible membrane remodulation. Further, this study identifies the possible roles of GHs, flagellar assembly, chemotaxis and production of wetting agents and surfactants in swarming motility along with the validation from gene expression using RT-PCR. [doi:10.25345/C5H306] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Paenibacillus polymyxa, proteomics, lipidomics, bioinformatics, swarming, swimming, Glycoside hydrolase, polyketide synthase, surfactant, flagella, chemotaxis, lantibiotics

Contact

Principal Investigators:
(in alphabetical order) 		Robert L. Hettich, Oak Ridge National Laboratory, United States
Submitting User: spoudel
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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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