Cell lysate from HAP1 cells were separated on several columns, the proteins were digested with trypsin and analysed on a Q Exactive HF-X instrument.
[doi:10.25345/C55X71]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: E3 Ubiquitin Ligase ; FBXO7 ; NF-kB
Principal Investigators: (in alphabetical order) |
Bertrand Fabre, Techinion, Israel |
Submitting User: | bertrandfabre31 |
Udasin RG, Gottfried Y, Fabre B, Bercovich B, Ziv T, Ciechanover A.
The p105 NF-?B precursor is a pseudo substrate of the ubiquitin ligase FBXO7, and its binding to the ligase stabilizes it and results in stimulated cell proliferation.
Biochem. Biophys. Res. Commun. Epub 2020 Sep 12.
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