MassIVE MSV000097432

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NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

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Description

WT-Mock-1: WT cells treated with vehicle for 24 hours, replicate-1: 126 WT-Mock-2: WT cells treated with vehicle for 24 hours, replicate-2: 127N WT-Mock-3: WT cells treated with vehicle for 24 hours, replicate-3: 127C WT-Mock-4: WT cells treated with vehicle for 24 hours, replicate-4: 128N WT-6-TG-1: WT cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-1: 128C WT-6-TG-2: WT cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-2: 129N WT-6-TG-3: WT cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-3: 129C WT-6-TG-4: WT cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-4: 130N NUDT5-Mock-1: NUDT5 KO cells treated with vehicle for 24 hours, replicate-1: 130C NUDT5-Mock-2: NUDT5 KO cells treated with vehicle for 24 hours, replicate-2: 131N NUDT5-Mock-3: NUDT5 KO cells treated with vehicle for 24 hours, replicate-3: 131C NUDT5-Mock-4: NUDT5 KO cells treated with vehicle for 24 hours, replicate-4: 132N NUDT5-6-TG-1: NUDT5 KO cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-1: 132C NUDT5-6-TG-2: NUDT5 KO cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-2: 133N NUDT5-6-TG-3: NUDT5 KO cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-3: 133C NUDT5-6-TG-4: NUDT5 KO cells treated with 0.5ug/mL 6-TG for 24 hours , replicate-4: 134N [doi:10.25345/C5MC8RV07] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Purine metabolism ; NUDT5 ; PPAT ; thiopurine ; DatasetType:Proteomics

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Principal Investigators:
(in alphabetical order) 		Ralph DeBerardinis, UT Southwestern, United States
Submitting User: alemoff
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