MassIVE MSV000092187

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Effects of the chlorophyll derivative 132-hydroxypheophytine a on zebrafish metabolomics

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Description

Zebrafish larvae were exposed from 3 DPF to 5 DPF to the chlorophyll derivative 13-2-hydroxypheophytine a. Metabolites were extracted with some modification of the protocol published by Lin et al 2019 (10.1016/j.bbrc.2019.04.003.). 3 experimental groups: DMSO 0.1% (solvent control) and hpa at 7.5 ug/ml (hpa1) and at 15 ug/ml (hpa2). All details can be found in the paper that published this data set. Title: Insights into the mechanism of action of the chlorophyll derivative 132-hydroxypheophytine a on reducing neutral lipid reserves in zebrafish larvae and mice adipocytes Authors: Ana Carrasco del Amor, Rene Hernandez Butista, Siegfried Ussar, Susana Cristobal, Ralph Urbatzka European Journal of Pharmacology accepted: 10/24/2023 doi: 10.1016/j.ejphar.2023.176158 [doi:10.25345/C5TT4G397] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: metabolomics ; zebrafish larvae 5 DPF ; chlorophyll derivative

Contact

Principal Investigators:
(in alphabetical order) 		Ralph Urbatzka, CIIMAR, Portugal
Submitting User: rurbatzka

Publications

Carrasco Del Amor A, Butista RH, Ussar S, Cristobal S, Urbatzka R.
Insights into the mechanism of action of the chlorophyll derivative 13-2-hydroxypheophytine a on reducing neutral lipid reserves in zebrafish larvae and mice adipocytes.
Eur J Pharmacol. Epub 2023 Oct 26. doi: 10.1016/j.ejphar.2023.176158.

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