MassIVE MSV000088765

Partial Public

ADAP1 promotes latent HIV 1 reactivation by selectively tuning KRAS ERK AP 1 T cell signaling-transcriptional axis

Description

Human primary CD4plus T cells resting and TCR CD28 stimulated for 1 hour, 843774 0hr rep1 ADAP1, 843775 0hr rep2 ADAP1, 843776 0hr rep3 ADAP1, 843780 1hr rep1 ADAP1, 843781 1hr rep2 ADAP1, 843872 1hr rep2 ADAP1, 820052 0hr IgG, 820053 0hr ADAP1, 820054 1hr IgG, 820055 1hr ADAP1. [doi:10.25345/C57W11] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: latency ; ADAP1 ; KRAS ; cell signaling ; genetic screen ; HIV 1 ; CD4 T cells

Contact

Principal Investigators:
(in alphabetical order)
Ivan D'Orso, University of Texas Southwestern Medical Center, USA
Submitting User: jjotto
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Experimental Design
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Identification Results
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Quantification Results
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Number of distinct conditions across all analyses (original submission and reanalyses) associated with this dataset.

Distinct condition labels are counted across all files submitted in the "Metadata" category having a "Condition" column in this dataset.

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Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

Distinct replicate labels are counted across all files submitted in the "Metadata" category having a "BioReplicate" or "Replicate" column in this dataset.

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Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

The technical replicate count is defined as the maximum number of times any one distinct combination of condition and biological replicate was analyzed across all files submitted in the "Metadata" category. In the case of fractionated experiments, only the first fraction is considered.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

"N/A" means no results of this type were submitted.
Number of distinct unmodified peptide sequences reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
This dataset may not contain all raw spectra data as originally deposited in PRIDE. It has been imported to MassIVE for reanalysis purposes, so its spectra data here may consist solely of processed peak lists suitable for reanalysis with most software.