MassIVE MSV000087870

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Primary villous trophoblasts exposed to flame retardant BDE-47

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Description

We exposed primary villous trophoblasts to flame retardant BDE-47 (1, 5 uM) across three culture time points (15, 24, 39 hr). [doi:10.25345/C5M82M] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: human, BDE-47, trophoblast, flame retardant

Contact

Principal Investigators:
(in alphabetical order) 		Susan Fisher, University of California San Francisco, United States of America
Submitting User: hchen2

Publications

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Proteomic analyses of primary human villous trophoblasts exposed to flame retardant BDE-47 using SWATH-MS.
Toxicology. 2023 Aug 1;494:153583. doi: 10.1016/j.tox.2023.153583. Epub 2023 Jun 28. PMID: 37385330; PMCID: PMC10864010.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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