MassIVE MSV000098216

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Variability of Micrurus venom from Bahia_Brazil

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Description

Coral snakes represent a highly diversified group of elapids in the New World. However, little is known about the diversity of coral snakes in the state of Bahia, making it essential to map their distribution and gain a better understanding of the variability in their venoms. Such knowledge is crucial not only for evolutionary and ecological studies but also for improving antivenom production and the clinical management of envenomations caused by these snakes. The MS data demonstrated in this study, the variation in the composition and activities of Micrurus venoms from the state of Bahia, Brazil, evidencing their diversity. Analysis through proteomic and functional studies of three different venom samples reveals differences in protein composition, which correlate with biological and enzymatic activities, as well as varying lethal potencies. [doi:10.25345/C5F18ST25] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Micrurus venom ; Coral snakes ; Variability ; Mass spectrometry ; DatasetType:Proteomics

Contact

Principal Investigators:
(in alphabetical order) 		Ilka Borges Biondi, Universidade Estadual de Feira de Santana (UEFS), Bahia (BA), Brazil
Luciana Casais-e-Silva, Department of Bioregulation, Institute of Health Sciences (ICS), Federal University of Bahia, Salvador, BA, Brazil
Lucilene Delazari dos Santos, Graduate Programs in Tropical Diseases and in Medical Biotechnology, Botucatu Medical School (FMB)/Biotechnological Institute (IBTEC), Sao Paulo State University (UNESP), Brazil
Submitting User: lucilene
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Number of distinct conditions across all analyses (original submission and reanalyses) associated with this dataset.

Distinct condition labels are counted across all files submitted in the "Metadata" category having a "Condition" column in this dataset.

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Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

Distinct replicate labels are counted across all files submitted in the "Metadata" category having a "BioReplicate" or "Replicate" column in this dataset.

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Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct unmodified peptide sequences reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
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