MassIVE MSV000093339

Partial Public PXD046795

Proteome analysis of the retina from RhoQ344X/+ mouse

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Description

Retinal proteomes from wild-type and RhoQ344X mutant mice at postnatal day 35 were analyzed by label-free quantitative proteomics to understand proteomic change caused by the rhodopsin mutation. [doi:10.25345/C5ST7F73J] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Mouse, retina, LC-MS/MS

Contact

Principal Investigators:
(in alphabetical order) 		Yoshikazu Imanishi, Indiana University School of Medicine, United States of America
Submitting User: ShimpeiTakita

Publications

Takita S, Jahan S, S Imanishi S, Harikrishnan H, LePage D, Mann RJ, Conlon RA, Miyagi M, Imanishi Y.
Rhodopsin mislocalization drives ciliary dysregulation in a novel autosomal dominant retinitis pigmentosa knock-in mouse model.
FASEB J. 2024 Apr 30;38(8):e23606.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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