MassIVE MSV000090908

Complete Public PXD038864

GSK-3 Interactomes from APMS and BioID

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Description

Interactomes of GSK-3 Isoforms compared by APMS (in HEK293) and BioID (in HEK293 and HeLa cells). [doi:10.25345/C59G5GJ7C] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Affinity purification ; BioID ; Proximity-dependent biotinylation ; Protein-protein interaction ; GSK-3 ; Isoform differentiation ; interactome

Contact

Principal Investigators:
(in alphabetical order) 		Jim Woodgett, Lunenfeld Tanenbaum Research Institute, Canada
Submitting User: jwoodgett

Publications

Cormier KW, Larsen B, Gingras AC, Woodgett JR.
Interactomes of Glycogen Synthase Kinase-3 Isoforms.
J Proteome Res. Epub 2023 Feb 13.

Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett.
Interactomes of Glycogen Synthase Kinase-3 Isoforms.
J. Proteome Res. 2023 (in preparation).

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Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

Distinct replicate labels are counted across all files submitted in the "Metadata" category having a "BioReplicate" or "Replicate" column in this dataset.

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Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

The technical replicate count is defined as the maximum number of times any one distinct combination of condition and biological replicate was analyzed across all files submitted in the "Metadata" category. In the case of fractionated experiments, only the first fraction is considered.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct unmodified peptide sequences reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
This dataset may not contain all raw spectra data as originally deposited in PRIDE. It has been imported to MassIVE for reanalysis purposes, so its spectra data here may consist solely of processed peak lists suitable for reanalysis with most software.