MassIVE MSV000086042

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A novel mechanism for NF-kB activation via IkB aggregation

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Description

Proteins which interact with IkBa in insoluble aggregates known as Mallory-Denk bodies were characterized by AP-MS, Biotinylation by antibody recognition (BAR), and LCMS analysis of detergent solubalized aggregates. See the supplementary table (S12) for file annotation. [doi:10.25345/C5ZN0R] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: affinity purification mass spectrometry ; biotinylation by antibody recognition ; protein aggregation ; inflammation ; mallory-denk body

Contact

Principal Investigators:
(in alphabetical order) 		Maria Almira Correia, UCSF, USA
Submitting User: mtrnka

Publications

Liu Y, Trnka MJ, Guan S, Kwon D, Kim DH, Chen JJ, Greer PA, Burlingame AL, Correia MA.
A Novel Mechanism For NF-?B Activation Via I?B Aggregation: Implications For Hepatic Mallory-Denk-Body Induced Inflammation.
Mol Cell Proteomics. Epub 2020 Sep 10.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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