MassIVE MSV000084260

Complete Public PXD015898

Time-Dependent Proteome Study: Human-in-mouse xenograft breast cancer tumor samples (0, 5, 30, 60 min)

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Description

The objective of the Time-Dependent Proteome Study was to evaluate changes in the proteome and phosphoproteome when there is a delay in freezing tissues following sample (tumor) excision. The biospecimens used are from human-in-mouse breast cancer tumor samples.
Ref: Mertins P et al., (2014) Mol Cell Proteomics, Apr 9. E-Publication

[doi:10.25345/C5894M] [dataset license: Custom User License]

Keywords: CPTAC

Contact

Principal Investigators:
(in alphabetical order) 		Daniel C Liebler, Vanderbilt University, USA
Forest White, Massachusetts Institute of Technology, N/A
Richard Smith, Pacific Northwest National Laboratory, USA
Steven A. Carr, Broad Institute of MIT and Harvard, United States
Xian Chen, University of North Carolina, USA
Submitting User: cptac

Publications

Mertins P, Yang F, Liu T, Mani DR, Petyuk VA, Gillette MA, Clauser KR, Qiao JW, Gritsenko MA, Moore RJ, Levine DA, Townsend R, Erdmann-Gilmore P, Snider JE, Davies SR, Ruggles KV, Fenyo D, Kitchens RT, Li S, Olvera N, Dao F, Rodriguez H, Chan DW, Liebler D, White F, Rodland KD, Mills GB, Smith RD, Paulovich AG, Ellis M, Carr SA.
Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.
Mol. Cell Proteomics. 2014 Jul;13(7):1690-704. Epub 2014 Apr 9.

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