MassIVE MSV000086769

Partial Public

Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth

Description

Lysosomes were immuno-isolated from HEK293T cells and PaTu8988T pancreatic ductal adenocarcinoma cells and analyzed by mass spectrometry based proteomics. Three independent biological replicates for each cell line is provided. [doi:10.25345/C5KZ26] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: lysosome, pancreatic cancer, autophagy, myoferlin

Contact

Principal Investigators:
(in alphabetical order)
Rushika M. Perera, University of California, San Francisco, USA
Submitting User: rperera78

Publications

Gupta S, Yano J, Mercier V, Htwe HH, Shin HR, Rademaker G, Cakir Z, Ituarte T, Wen KW, Kim GE, Zoncu R, Roux A, Dawson DW, Perera RM.
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth.
Nat Cell Biol. 2021 Mar;23(3):232-242. Epub 2021 Mar 8.

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Identification Results
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Quantification Results
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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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