MassIVE MSV000082136

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The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h

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Description

Domain level interactions between the ISWI remodeler SNF2h and reconstituted mononucleosomes were probed by EDC crosslinking under different biochemical conditions: ADP, ADP-BeFx, ADP-BeFx with LANA peptide added (which binds at the acidic patch). A semi quantitative approach was used to monitor domain-domain interactions enriched during the remodeling cycle. [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: quantitative Crosslinking

Contact

Principal Investigators:
(in alphabetical order) 		Geeta Narlikar, University of California San Francisco, USA
Submitting User: mtrnka

Publications

Gamarra N, Johnson SL, Trnka MJ, Burlingame AL, Narlikar GJ.
The nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h.
Elife. Epub 2018 Apr 17.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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