MassIVE MSV000094706

Partial Public PXD052093

DiazMeco_Increased translation driven by a non-canonical EZH2 cistrome creates a synthetic vulnerability in enzalutamide-resistant prostate cancer_set3

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Description

Identification of phosphopeptides EZH2 in control and kinase-deficient cells. The HA-EZH2 plasmid was transfected in HEK 293T cells, and HA-EZH2 was subsequently purified using HA peptide. The elution was performed with 1mg/mL HA-peptide in Tris buffered saline (TBS with 150mM NaCl), pH 7.5 in a final volume of 100 microL and a concentration of 150-250 ng/microL. Two samples were sent to the facility for analysis: HEK293T-sgC and sgPRKCI. [doi:10.25345/C5639KH0K] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: EZH2 ; PRKCI ; Prostate Cancer

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Principal Investigators:
(in alphabetical order) 		Maria T. Diaz-Meco Conde, WEILL CORNELL MEDICINE, United States
Submitting User: moscatdiazme
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