We have run shotgun proteomic analysis of lung proteome from mice with allergic asthma, influenza-induced exacerbation of asthma (or treated with dexamethasone) vs. healthy mice using LC-MS/MS. PRM proteomic analysis coupled with stable isotopic labelling was performed for quantification of protein STAT1. Protein digestion was done with Trypsin/Lys-C mix endoproteinase.
[doi:10.25345/C5QG4C]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: Proteome ; LC-MS/MS ; Shotgun proteomics ; Label-free quantification ; PRM proteomic ; STAT1 quantification ; Influenza-induced asthma exacerbation ; Steroid-resistant asthma
Principal Investigators: (in alphabetical order) |
Xiang Li, The University of Newcastle, Australia Xiaoming Liu, University of Newcastle, Australia |
Submitting User: | Xiang |
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