We employed isobaric labeled peptides to do bottom-up proteomics to quantify both non-enriched total peptides and enriched phospho-peptides obtained from hearts of control mice expressing wild-type cardiac troponin I and transgenic mice expressing the truncated N-terminal cardiac troponin I.
[doi:10.25345/C5Q80S]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: Sarcomeres ; Paxillin ; Cytoskeleton ; Integrin ; Heart ; Mouse
Principal Investigators: (in alphabetical order) |
R. John Solaro, University of Illinois-Chicago, USA |
Submitting User: | cmwarren_8 |
Warren CM, Halas M, Goldspink PH, Feng HZ, Herren AW, Wolska BM, de Tombe PP, Jin JP, Solaro RJ.
Truncation of the N-terminus of cardiac troponin I initiates adaptive remodeling of the myocardial proteosome via phosphorylation of mechano-sensitive signaling pathways.
Mol Cell Biochem. 2022 Jun;477(6):1803-1815. Epub 2022 Mar 22.
Number of Files: | |
Total Size: | |
Spectra: | |
Subscribers: | |
Owner | Reanalyses | |
---|---|---|
Experimental Design | ||
Conditions:
|
||
Biological Replicates:
|
||
Technical Replicates:
|
||
Identification Results | ||
Proteins (Human, Remapped):
|
||
Proteins (Reported):
|
||
Peptides:
|
||
Variant Peptides:
|
||
PSMs:
|
||
Quantification Results | ||
Differential Proteins:
|
||
Quantified Proteins:
|
||
Browse Dataset Files | |
FTP Download Link (click to copy):
|