MassIVE MSV000091592

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Melanopsin (OPN4) is a novel player in skin homeostasis and attenuates UVA-induced effects

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Description

The presence of melanopsin (OPN4) has been shown in cultured murine melanocytes and was associated with ultraviolet A radiation (UVA) reception. We demonstrated the protective role of OPN4 in skin physiology and the increased UVA-induced damage in its absence using proteomics analysis. [doi:10.25345/C5Q23R93F] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Melanopsin ; UVA radiation ; Skin

Contact

Principal Investigators:
(in alphabetical order) 		Ana Maria L Castrucci, University of Sao Paulo, Brazil
Jose Thalles Lacerda, University of Sao Paulo, Brazil
Submitting User: jthalles

Publications

Sua-Cespedes C, Lacerda JT, Zanetti G, David DD, Moraes MN, de Assis LVM, Castrucci AML.
Melanopsin (OPN4) is a novel player in skin homeostasis and attenuates UVA-induced effects.
J Photochem Photobiol B. Epub 2023 Mar 28.

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