MassIVE MSV000089272

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EGFR ligand shifts the role of EGFR from oncogene to tumor suppressor in EGFR amplified glioblastoma by suppressing invasion through BIN3 upregulation

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Description

For LUM2_529995_Vehicle_24 and LUM2_529996_EGF_24, GBM12 cells were treated with vehicle or EGF for 24 hours, cells lysates were immunoprecipitated by BIN3 antibody and subjected to Mass spectrometry (MS) analysis. For LUM2_626031_Vehicle_0pt5 and LUM2_626032_EGF_0pt5, GBM12 cells were treated with vehicle or EGF for 30 minutes, cells lysates were immunoprecipitated by EGFR antibody and subjected to Mass spectrometry (MS) analysis. [doi:10.25345/C5WH2DJ52] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: EGFR ; BIN3 ; EGF ; GBM ; invasion ; oncogene ; tumor suppressor

Contact

Principal Investigators:
(in alphabetical order) 		Amyn A. Habib, University of Texas Southwestern Medical Center, USA
Submitting User: jjotto
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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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