MassIVE MSV000095675

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Consistent Amyloid Fibril Structures Across Multiple Organs and Patients in ATTRv-T60A Amyloidosis Revealed by Cryo-EM

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Description

Cardiac ATTRv-T60A amyloid fibrils from three different patients, and ATTRv-T60A fibrils from thyroid, explanted kidney, and explanted liver from one of the patients (tissues obtained from autopsy and transplant surgery). Identification of tryptic and non-tryptic fragments in ATTRv-V30M). Cardiac ATTR fibrils (patient 1): Sample ID: 1176938 Cardiac ATTR fibrils (patient 2): Sample ID: 1176937 Cardiac ATTR fibrils from (patient 3): Sample ID: 1176932 Thyroid ATTR fibrils from (patient 3): Sample ID: 1176934 Renal ATTR fibrils from (patient 3): Sample ID: 1176933 Hepatic ATTR fibrils from (patient 3): Sample ID: 1176935 [doi:10.25345/C5R20S76K] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Transthyretin ; Amyloidosis ; ATTR

Contact

Principal Investigators:
(in alphabetical order) 		Lorena Saelices Gomez, UT Southwestern Medical Center, United States
Submitting User: alemoff
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