MassIVE MSV000090289

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Proteomic analysis indicates that Cav-1 regulates mitochondria and cellular metabolism pathways in hippocampal NSPCs

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Description

To investigate the mechanisms underlying Cav-1 regulation of NSPCs, we used quantitative proteomics to assess protein alterations in response to Cav-1 deletion in primary hippocampal NSPCs. Due to our findings that Cav-1 deletion in NSPCs reduces proliferation, we hypothesized that Cav-1 regulates proteins and pathways involved cell cycle dynamics and proliferation. [doi:10.25345/C55X25H8S] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: caveolin-1 ; mitochondria ; cellular metabolism ; hippocampus

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Principal Investigators:
(in alphabetical order) 		Stephanie Cologna, University of Illinois at Chicago, USA
Submitting User: jklwp007
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