MassIVE MSV000090262

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Phosphorylation in the Hippocampal Tissue of 3-week NPC1-null Mice

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Description

TMT10plex-labeled, phospho-enriched, fractionated sample from the hippocampus of the NPC1-null mouse model was collected using nanoflow-LC-MS. Our goal is to identify signaling changes at an early time-point in the NPC1-null mouse model. [doi:10.25345/C5ST7F21B] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Phosphorylation ; NPC1 ; Niemann-Pick Disease Type C ; Proteomics ; TMT10plex

Contact

Principal Investigators:
(in alphabetical order) 		Stephanie Cologna, University of Illinois at Chicago, USA
Submitting User: tnguy214

Publications

Nguyen TTA, Mohanty V, Yan Y, Francis KR, Cologna SM.
Comparative Hippocampal Proteome and Phosphoproteome in a Niemann-Pick, Type C1 Mouse Model Reveal Insights into Disease Mechanisms.
J Proteome Res. 2024 Jan 5;23(1):84-94. Epub 2023 Nov 24.

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