TMT10plex-labeled, phospho-enriched, fractionated sample from the hippocampus of the NPC1-null mouse model was collected using nanoflow-LC-MS. Our goal is to identify signaling changes at an early time-point in the NPC1-null mouse model.
[doi:10.25345/C5ST7F21B]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: Phosphorylation ; NPC1 ; Niemann-Pick Disease Type C ; Proteomics ; TMT10plex
Principal Investigators: (in alphabetical order) |
Stephanie Cologna, University of Illinois at Chicago, USA |
Submitting User: | tnguy214 |
Nguyen TTA, Mohanty V, Yan Y, Francis KR, Cologna SM.
Comparative Hippocampal Proteome and Phosphoproteome in a Niemann-Pick, Type C1 Mouse Model Reveal Insights into Disease Mechanisms.
J Proteome Res. 2024 Jan 5;23(1):84-94. Epub 2023 Nov 24.
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