MassIVE MSV000090202

Partial Public

Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.

Description

Supporting data for "Disruption of lysosomal proteolysis in astrocytes facilitates midbrain proteostasis failure in an early-onset PD model", DOI: T.B.D. Related to Figure 4A and S4A-B. KN43-66 - TMTpro | 4plex | Whole cell proteome - MS3 KN67-72 - TMTpro | 4plex | Enriched Phospho-peptides - MS2 KN73-96 - TMT | 9plex | Whole cell proteome - MS2 [doi:10.25345/C5BV7B05F] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: TMT ; TMTpro

Contact

Principal Investigators:
(in alphabetical order)
Alban Ordureau, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, USA
Submitting User: aordureau

Publications

Morrone Parfitt G, Coccia E, Goldman C, Whitney K, Reyes R, Sarrafha L, Nam KH, Sohail S, Jones DR, Crary JF, Ordureau A, Blanchard J, Ahfeldt T.
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson's disease model.
Nat Commun. 2024 Jan 10;15(1):447. Epub 2024 Jan 10.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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