MassIVE MSV000090888

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GNPS - Inducible antimicrobial activity in Bacillus spp

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Description

In previous research, we have discovered a phenomenon of inducible antagonistic activity in strains of the order Bacillales in which, large inhibition zones were produced against different pathogens when growing in the presence of the chemical compound triphenyl tetrazolium chloride (TTC), where Bacillus subtilis NCIB3610, Bacillus cereus EA-CB1047 and B. tequilensis EA-CB0015 how high activity against the phytopathogen Ralstonia solanacearum. The exact structure of these compounds has not been so far elucidated; therefore, this project aims to clarify whether the changes in the metabolic profiles of Bacillus sp. correspond to biotransformation reactions of TTC or might be products of any additional biosynthetic process not yet revealed, using molecular networks approaches. [doi:10.25345/C5154DT56] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Tetrazolium salt ; Bacillus subtilis ; Bacillus cereus ; Ralstonia solanacerum ; Bacillus tequilensis

Contact

Principal Investigators:
(in alphabetical order) 		Valeska Villegas, Universidad EAFIT, Colombia
Submitting User: amcaraballor
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GNPS content goes here (MSV000090888 [task=8a2b261e8d1f4283aae2f80f088e54b9])
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Number of distinct conditions across all analyses (original submission and reanalyses) associated with this dataset.

Distinct condition labels are counted across all files submitted in the "Metadata" category having a "Condition" column in this dataset.

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Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

Distinct replicate labels are counted across all files submitted in the "Metadata" category having a "BioReplicate" or "Replicate" column in this dataset.

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Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

The technical replicate count is defined as the maximum number of times any one distinct combination of condition and biological replicate was analyzed across all files submitted in the "Metadata" category. In the case of fractionated experiments, only the first fraction is considered.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct unmodified peptide sequences reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
This dataset may not contain all raw spectra data as originally deposited in PRIDE. It has been imported to MassIVE for reanalysis purposes, so its spectra data here may consist solely of processed peak lists suitable for reanalysis with most software.