MassIVE MSV000081185

Complete Public PXD006782

Mechanisms connecting the conserved protein kinases Kin1, Pom1, and Ssp1 in fission yeast cell polarity and division

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Description

Connections between the protein kinases that function within complex cell polarity networks are poorly understood. Rod-shaped fission yeast cells grow in a highly polarized manner, and genetic screens have identified many protein kinases required for polarized growth and cell shape. Kin1, the sole MARK/PAR-1 family kinase in fission yeast, regulates cell polarity and cytokinesis through unknown mechanisms. We performed a large-scale phosphoproteomics screen to identify and characterize Kin1 substrates in cells. [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Kin1 ; Pom1 ; Ssp1 ; MARK/PAR1 ; cell polarity ; cytokinesis ; protein kinase ; phosphoproteomics

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Principal Investigators:
(in alphabetical order) 		Arminja Kettenbach, The Geisel School of Medicine at Dartmouth, United States
Submitting User: madamo
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