Intraocular pressure was elevated through episkleral vein occlusion by thermic cauterization of SD rats. Animals were further sacrificed after different periods of elevated IOP and the retinal proteins were investigated for alterations regarding the relative protein level in this experimental model of glaucoma.
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: Retina ; glaucoma ; crystallins ; proteomics ; ocular hypertension
Principal Investigators: (in alphabetical order) |
PD Dr. Verena Prokosch, Experimental Ophthalmology, Department of Ophthalmology, Mainz, Rheinland-Pfalz, Germany, N/A |
Submitting User: | ccms |
Anders F, Teister J, Liu A, Funke S, Grus FH, Thanos S, von Pein HD, Pfeiffer N, Prokosch V.
Intravitreal injection of ?-crystallin B2 improves retinal ganglion cell survival in an experimental animal model of glaucoma.
PLoS ONE. 2017;12(4):e0175451. Epub 2017 Apr 6.
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