MassIVE MSV000087636

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The Vibrio vulnificus stressosome: an oxygen-sensor involved in regulating iron metabolism

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Description

Stressosomes are stress-sensing protein complexes widely conserved among bacteria. Although a role in the regulation of the general stress response is well documented in Gram-positive bacteria, the activating signals are still unclear, and little is known about the physiological function of stressosomes in the Gram-negative bacteria. Here we investigated the stressosome of the Gram-negative, marine pathogen Vibrio vulnificus. We demonstrate that it senses oxygen and identified its role in modulating iron-metabolism. [doi:10.25345/C5681H] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: stressosome ; iron-metabolism ; Gram-negative ; stress sensing

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Principal Investigators:
(in alphabetical order) 		Jan Pane-Farre, Center for synthetic Microbiology (SYNMIKRO) & Department of Chemistry, Philipps- University Marburg, Hans-Meerwein-Strasse 6, 35043 Marburg, Germany
Submitting User: stemicha
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