MassIVE MSV000092565

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Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons

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Description

Supporting TMT MS data for paper (doi: 10.1016/j.neuron.2021.12.029) by Goldsmith J. et al., titled "Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons". Index of RAW files uploaded: AO3068-3079: Fractionated (12 fractions) Autophagosome Proteome Profiling (Unimod: 35; 737; 4)). Five replicates of autophagosome prep treated or not with Proteinase K. TMT: 126 (G3_01); 127n (G3+PK_01); 127c (G3_02); 128n (G3+PK_02); 128c (G3_03); 129n (G3+PK_03); 129c (G3_04); 130n (G3+PK_04); 130c (G3_05); 131n (G3+PK_05). [doi:10.25345/C5FJ29P7W] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: TMT ; autophagy ; Neuronal homeostasis

Contact

Principal Investigators:
(in alphabetical order) 		Alban Ordureau, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, USA
Submitting User: aordureau

Publications

Goldsmith J, Ordureau A, Harper JW, Holzbaur ELF.
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons.
Neuron. 2022 Mar 16;110(6):967-976.e8. Epub 2022 Jan 19.

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