MassIVE MSV000098984

Partial Public PXD067902

Proteomic Profiling of EUS-FNA Samples Differentiates PDAC and MFP

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Description

Mass-forming chronic pancreatitis (MFP) and pancreatic ductal adenocarcinoma (PDAC) can present with overlapping radiological, clinical, and serological features in patients with underlying chronic pancreatitis (CP), making differential diagnosis particularly challenging. Current diagnostic tools, including CA19-9 and endoscopic ultrasound (EUS) imaging, often lack the specificity needed to reliably distinguish between these conditions. The objective of this study was to investigate whether proteomic profiling of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) samples could provide molecu-lar-level discrimination between MFP and PDAC in patients with CP. [doi:10.25345/C5MG7G81F] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: label-free proteomics ; mass-forming pancreatitis ; pancreatic ductal adenocarcinoma ; EUS-FNA ; DatasetType:Proteomics

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Principal Investigators:
(in alphabetical order) 		Iuga Cristina-Adela, MEDFUTURE Research Center for Advanced Medicine, Romania
Submitting User: ioanapralea
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