This dataset contains raw mass spectrometry data (in the form of Thermo Fisher .RAW files) supporting associated publication “Variable blood processing procedures contribute to plasma proteomic variability” by Halvey et al.
The experiments characterized by these data evaluated effects on human plasma proteome of the following factors involved in blood to plasma processing: delay to the first centrifugation, temperature and type of anticoagulant tube. Each combination of these factors has been applied to samples from n=4 healthy volunteers. Sample annotation provided in the file “Blood_to_Plasma_Processing_Sample_Annotation.txt” maps each sample to combination of those factors and anonymous subject identifier.
For “Experiment5” there were several instances of LC-MS/MS analytical replicates for this sample. It should be noted that for this experiment the .RAW file from the “./updates/2020-08-03_vfarutin_e264fbfc/raw/” folder under this dataset FTP address represents the actual LC-MS/MS run used to generate the data in the associated paper by Halvey et al.
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: blood ; plasma ; time ; temperature ; anticoagulant ; heparin ; EDTA
Principal Investigators: (in alphabetical order) |
Anthony M. Manning, Momenta Pharmaceuticals, Inc., USA |
Submitting User: | vfarutin |
Halvey P, Farutin V, Koppes L, Gunay NS, Pappas DA, Manning AM, Capila I.
Variable blood processing procedures contribute to plasma proteomic variability.
Clin Proteomics. 2021 Jan 19;18(1):5. Epub 2021 Jan 19.
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