MassIVE MSV000088393

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OGT controls mammalian cell viability by regulating the proteasome/mTOR/mitochondrial axis

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Description

TMT-based proteomic and phosphoproteomic analysis of mouse embryonic stem cells upon deletion of Ogt. [doi:10.25345/C5XZ9Z] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Genome-wide CRISPR/Cas9 screen ; mouse embryonic stem cells ; mechanistic target of rapamycin ; ubiquitin-dependent protein degradation ; amino acids

Contact

Principal Investigators:
(in alphabetical order) 		Anjana Rao, La Jolla Institute for Immunology, United States
Submitting User: sammyers

Publications

Li X, Yue X, Sepulveda H, Burt RA, Scott DA, A Carr S, A Myers S, Rao A.
OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis.
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218332120. Epub 2023 Jan 10.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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