Histones were isolated from brown adipose tissue and liver from mice housed at 28, 22, or 8 C. Quantitative top- or middle-down approaches were used to quantitate histone H4 and H3.2 proteoforms. See published article for complimentary RNA-seq and RRBS datasets.
[doi:10.25345/C5F18SR28]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: brown adipose tissue ; histone ; proteoform
Principal Investigators: (in alphabetical order) |
Nicolas L. Young, Baylor College of Medicine, USA |
Submitting User: | btaylor |
Taylor BC, Steinthal LH, Dias M, Yalamanchili HK, Ochsner SA, Zapata GE, Mehta NR, McKenna NJ, Young NL, Nuotio-Antar AM.
Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress.
Epigenetics Chromatin. 2024 Apr 27;17(1):12. Epub 2024 Apr 27.
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