MassIVE MSV000093136

Complete Public PXD046200

Signatures of Cysteine Oxidation on Structural and Contractile Proteins Are Associated with Physical Performance and Muscle Function in Older Adults

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Description

Human muscle biopsies from older adults were processed with a redox proteomics workflow and analyzed by LC-MS/MS with TMT based quantification. [doi:10.25345/C51G0J53Z] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: muscle ; power ; fitness ; thiol oxidation ; post-translational modifications ; redox

Contact

Principal Investigators:
(in alphabetical order) 		Wei-Jun Qian, Pacific Northwest National Laboratory, United States
Submitting User: alchemistmatt

Publications

Day NJ, Kelly SS, Lui LY, Mansfield TA, Gaffrey MJ, Trejo JB, Sagendorf TJ, Attah IK, Moore RJ, Douglas CM, Newman AB, Kritchevsky SB, Kramer PA, Marcinek DJ, Coen PM, Goodpaster BH, Hepple RT, Cawthon PM, Petyuk VA, Esser KA, Qian WJ, Cummings SR.
Signatures of cysteine oxidation on muscle structural and contractile proteins are associated with physical performance and muscle function in older adults: Study of Muscle, Mobility and Aging (SOMMA).
Aging Cell. Epub 2024 Feb 8.

Day NJ, Kelly SS, Lui LY, Mansfield TA, Gaffrey MJ, Trejo JB, Sagendorf TJ, Attah K, Moore RJ, Douglas CM, Newman AB, Kritchevsky SB, Kramer PA, Marcinek DJ, Coen PM, Goodpaster BH, Hepple RT, Cawthon PM, Petyuk VA, Esser KA, Qian WJ, Cummings SR.
Signatures of Cysteine Oxidation on Muscle Structural and Contractile Proteins Are Associated with Physical Performance and Muscle Function in Older Adults: Study of Muscle, Mobility and Aging (SOMMA).
medRxiv. Epub 2023 Nov 8.

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