MassIVE MSV000095199

Partial Public PXD053527

LC/MS analysis for proteome of SHSY5Y induced by a beta

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Description

To explore the physiological mechanism of A beta in vitro, we employed mass spectrometry to investigate the altered proteomic events induced by lower submicromolar concentration of A beta. Human neuroblastoma SH-SY5Y cells were incubated with five different concentrations of A beta1-40 monomers and collected at four time points. The proteomic results found the time-course behavior of proteins involved in biological processes, such as RNA splicing, nuclear transport and protein localization. [doi:10.25345/C5GX4558V] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Alzheimer ; a beta

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Principal Investigators:
(in alphabetical order) 		chenxi yang, Southeast University, China
Submitting User: hubxfcxy1987
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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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