MassIVE MSV000085945

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Pathogenic human tau in the Line 66 model of frontotemporal dementia

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Description

Transgenic human tau in subcellular fractions extracted after electrophoresis of L66 mouse brain extract. For higher sequence coverage trypsin (Tr) and thermolysin (TL) digests were analysed. [doi:10.25345/C5NT93] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: Tau protein ; FTD ; L66 mice ; subcellular fractionation

Contact

Principal Investigators:
(in alphabetical order) 		Karima Schwab, Charite Universitaetsmedizin Berlin, Germany
Submitting User: Nlemke

Publications

Lemke N, Melis V, Lauer D, Magbagbeolu M, Neumann B, Harrington CR, Riedel G, Wischik CM, Theuring F, Schwab K.
Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia.
J Biol Chem. Epub 2020 Oct 30.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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