MassIVE MSV000098220

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Structural Polymorphism of ALECT2 Amyloid Fibrils Revealed by Cryo-EM: Implications for Disease Pathogenesis

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Description

1. Identification of tryptic and chymotryptic fragments in ALECT2 fibrils (Figure 1, Q Exactive HF) For tryptic: Sample ID 1176342 For Chymotryptic: Sample ID 1176352 2. Intact mass analysis of ALECT2 fibrils from the kidney (Supplementary figure 1 and supplementary table 1, X500B QTOF) Sample ID: 1176340 3. Post translational modification analysis of ALECT2 fibrils (Supplementary table 2, Oribtrap Fusion Lumos) Sample IDs: 1196735, 1196736 [doi:10.25345/C5SB3XB4T] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: ALECT2 ; amyloid ; kidney ; DatasetType:Proteomics

Contact

Principal Investigators:
(in alphabetical order) 		Lorena Saelices Gomez, UT Southwestern Medical Center, United States
Submitting User: alemoff
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