MassIVE MSV000087310

Complete Public PXD025648

Enterically derived high density lipoprotein restrains liver injury via the portal vein

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Description

The proteomes of HDL subspecies, HDL2 and HDL3, from pooled human serum purified by density gradient centrifugation were generated and compared to the proteomes of HDL2 and HDL3 derived from tportal venouhe s and antecubital venous blood matched across these two locations from the same individual. The latter were purified by size exclusion chromatography coupled with immunoprecipitation with anti-apoA1 mAb. [doi:10.25345/C5450G] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: High density lipoprotein ; lipoprotein

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Principal Investigators:
(in alphabetical order) 		Gwendalyn J. Randolph, PhD, Washington University School of Medicine in Saint Louis, USA
Submitting User: jmalone
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Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

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Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
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