Description
Paper submitted to Nature Communications (2021):
"Pseudomonas aeruginosa PA14 biofilms produce R-bodies, extendable protein polymers with roles in host colonization and virulence."
Abstract:
We used a modified R-body enrichment protocol to isolate SDS-insoluble fractions from PA14 biofilms and performed protein mass spectrometry (MS). We detected products of the reb cluster by MS. RebP1 and RebP2, which were detected in a ~1:1 ratio, were among the 12 most abundant proteins in our sample.
List of Files:
Q Exactive HF
Delta pel1
LD1_123015_012016_98min_5uL_1.raw
Delta pel2
LD2_123015_012016_98min_5uL_1.raw
WT
LD3_123015_98min_12uL_1_160120171453.raw
Synapt G2
Delta pel1
LD1_123015_011316_5uL_1.raw
LD1_123015_011316_5uL_2.raw
Delta pel2
LD2_123015_011316_5uL_1.raw
LD2_123015_011316_5uL_2.raw
WT
LD3_123015_011316_5uL_3.raw
LD3_123015_011316_5uL_4.raw
[doi:10.25345/C5GJ71]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: R-body, RebP1, RebP2
Contact
Principal Investigators:
(in alphabetical order)
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Lars Dietrich, Columbia University, United States
Lewis M. Brown, Columbia University, United States
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cuproteomics
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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis
of Quantified Analytes" category having a "Protein" column in this dataset.
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Number of distinct proteins found to be differentially abundant in at least one comparison
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A protein is differentially abundant if its change in abundance across conditions is found
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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis
of Quantified Analytes" category having a "Protein" column in this dataset.
"N/A" means no results of this type were submitted.
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