5-week old male and female Swiss Webster mice were infected with 500,000 Trypanosoma cruzi strain Sylvio X/104 parasites. Urine was collected from uninfected mice pre-infection, from infected and uninfected mice every week for 5 weeks post infection, from infected and uninfected mice 67 (females)/68 (males) days post infection, and from infected and uninfected mice 117 (females)/124 (males) days post infection for acute, mid-chronic, and chronic time-points. Metabolites were extracted with methanol and a targeted PRM LCMS analysis was ran on a Thermo Q Exactive Plus instrument with a Phenomenex Luna Omega Polar C18 column.
[doi:10.25345/C5TM7247T]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: T. cruzi ; LCMS ; Q Exactive ; Targeted ; PRM ; metabolomics ; mice
Principal Investigators: (in alphabetical order) |
Laura Isobel McCall, University of Oklahoma, USA |
Submitting User: | mccall_lab |
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Owner | Reanalyses | |
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