MassIVE MSV000089866

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Fallopian tube secreted proteins affect ovarian metabolites in high grade serous ovarian cancer

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Description

Data files from Q Exactive were imported into Proteome Discoverer (version 2.2, Thermo Fisher) and analyzed using a label-free quantitation method. For MOE PTENshRNA protein IDs, MOE PTENshRNA results were compared to MOE SCRshRNA results against a Mus musculus database (10090_20160912 fasta file) and a contaminants database with a false discovery rate (FDR) at 1% and Percolator. SKOV3 results were run against a Homo sapiens database (9606_20190612 fasta file)and a contaminants database (2015_5 fasta file). Each was analyzed with a FDR at 1% and a Target Decoy. [doi:10.25345/C5WH2DJ8H] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: SPARC ; Ovarian cancer

Contact

Principal Investigators:
(in alphabetical order) 		Joanna Burdette, University of Illinois at Chicago, USA
Laura M Sanchez, University of California, Santa Cruz, USA
Submitting User: l2sanchez

Publications

Tova M Bergsten, Sarah E Levy, Katherine E Zink, Hannah J Lusk, Melissa R Pergande, Stephanie M Cologna, Joanna E Burdette, Laura M Sanchez.
Fallopian tube secreted protein affects ovarian metabolites in high grade serous ovarian cancer.
Front Cell Dev Biol . 2022 Nov 7;10:1042734. doi: 10.3389/fcell.2022.1042734.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
This dataset may not contain all raw spectra data as originally deposited in PRIDE. It has been imported to MassIVE for reanalysis purposes, so its spectra data here may consist solely of processed peak lists suitable for reanalysis with most software.