MassIVE MSV000085123

Partial Public

GNPS - Microbispora corallina and Nonomuraea

Description

LC-MSMS analyses of extract coltures of Microbispora corallina producing the lantibiotic NAI-107 (aka microbisporicin) and Nonomuraea sp. ATCC39727 producing the glycopeptide A40926 [doi:10.25345/C50M60] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: NAI-107, lantibiotic, A40926, glycopeptide

Contact

Principal Investigators:
(in alphabetical order)
Marianna Iorio, NAICONS srl, Italy
Submitting User: SoniaMaffioli

Publications

Maffioli SI, Iorio M, Sosio M, Monciardini P, Gaspari E, Donadio S.
Characterization of the congeners in the lantibiotic NAI-107 complex.
J. Nat. Prod. 2014 Jan 24;77(1):79-84. Epub 2014 Jan 14.

Foulston LC, Bibb MJ.
Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes.
Proc. Natl. Acad. Sci. U.S.A. 2010 Jul 27;107(30):13461-6. Epub 2010 Jul 13.

Sosio M, Gallo G, Pozzi R, Serina S, Monciardini P, Bera A, Stegmann E, Weber T.
Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024, Producing the Lantibiotic NAI-107.
Genome Announc. Epub 2014 Jan 23.

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The Gene Cluster for the Biosynthesis of the Glycopeptide Antibiotic A40926 by Nonomuraea Species.
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Experimental Design
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Identification Results
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    Peptides:
    Variant Peptides:
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Quantification Results
    Differential Proteins:
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GNPS content goes here (MSV000085123 [task=38c1181ee521449382ca81efa84a6e81])
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Number of distinct conditions across all analyses (original submission and reanalyses) associated with this dataset.

Distinct condition labels are counted across all files submitted in the "Metadata" category having a "Condition" column in this dataset.

"N/A" means no results of this type were submitted.
Number of distinct biological replicates across all analyses (original submission and reanalyses) associated with this dataset.

Distinct replicate labels are counted across all files submitted in the "Metadata" category having a "BioReplicate" or "Replicate" column in this dataset.

"N/A" means no results of this type were submitted.
Number of distinct technical replicates across all analyses (original submission and reanalyses) associated with this dataset.

The technical replicate count is defined as the maximum number of times any one distinct combination of condition and biological replicate was analyzed across all files submitted in the "Metadata" category. In the case of fractionated experiments, only the first fraction is considered.

"N/A" means no results of this type were submitted.
Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.

"N/A" means no results of this type were submitted.
Number of distinct protein accessions reported across all analyses (original submission and reanalyses) associated with this dataset.

"N/A" means no results of this type were submitted.
Number of distinct unmodified peptide sequences reported across all analyses (original submission and reanalyses) associated with this dataset.

"N/A" means no results of this type were submitted.
Number of distinct peptide sequences (including modified variants or peptidoforms) reported across all analyses (original submission and reanalyses) associated with this dataset.

"N/A" means no results of this type were submitted.
Total number of peptide-spectrum matches (i.e. spectrum identifications) reported across all analyses (original submission and reanalyses) associated with this dataset.

"N/A" means no results of this type were submitted.
Number of distinct proteins quantified across all analyses (original submission and reanalyses) associated with this dataset.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
Number of distinct proteins found to be differentially abundant in at least one comparison across all analyses (original submission and reanalyses) associated with this dataset.

A protein is differentially abundant if its change in abundance across conditions is found to be statistically significant with an adjusted p-value <= 0.05 and lists no issues associated with statistical tests for differential abundance.

Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

"N/A" means no results of this type were submitted.
This dataset may not contain all raw spectra data as originally deposited in PRIDE. It has been imported to MassIVE for reanalysis purposes, so its spectra data here may consist solely of processed peak lists suitable for reanalysis with most software.