Dataset description
This dataset consists of 8 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 6600 mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by Ema Dreseris. BioID and Mass spectrometry acquisition was performed by Cassandra Wong. Analysis was performed by Cassandra Wong, Ema Dreseris, Anne-Claude Gingras and Eric Campos.
The files are associated with a manuscript submitted for publication by Karina Silveria et al. The main goal of this paper was to investigate CYP26B1 pathogenic variants reported by two families. This dataset comprehensively maps the interactome of CYP26B1 and the associated pathogenic variants using proximity labeling and affinity purification.
Peter Kannu is the corresponding author of the manuscript (kannu@ualberta.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
[doi:10.25345/C5TT4G378]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: CYP26B1 ; BioID ; Skeletal Dysplasia
Principal Investigators: (in alphabetical order) |
Anne-Claude Gingras, LTRI, Canada |
Submitting User: | gingraslab |
Karina C Silveira # 1, Inara Chacon Fonseca # 2, Connor Oborn 1, Parker Wengryn 1, Saima Ghafoor 1, Alexander Beke 1, Ema S Dreseris 3, Cassandra Wong 4, Aline Iacovone 5, Carrie-Lynn Soltys 1, Riyana Babul-Hirji 6, Osvaldo Artigalas 7, Arthur Antolini-Tavares 8, Anne-Claude Gingras 4 9, Eric Campos # 3 9, Denise P Cavalcanti # 10, Peter Kannu.
CYP26B1-related disorder: expanding the ends of the spectrum through clinical and molecular evidence.
Hum Genet . 2023 Nov;142(11):1571-1586. doi: 10.1007/s00439-023-02598-2. Epub 2023 Sep 27.
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Browse Dataset Files | Browse Results |
FTP Download Link (click to copy):
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