The impact of numerous diseases has been linked to differences in sex between organisms, including various neurological diseases. As neuropeptides are known to be key players in the nervous system, studying the variation of neuropeptidomic profiles between males and females in a crustacean model organism is of interest. By using high-resolution mass spectrometry with two complementary ionization sources in conjunction with quantitative chemical labeling, differences were observed in 5 key neural tissues and hemolymph.
[doi:10.25345/C5CF3J]
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: Male ; Female ; Crustacean ; Neuropeptides ; Mass Spectrometry ; Callinectes sapidus
Principal Investigators: (in alphabetical order) |
Lingjun Li, University of Wisconsin-Madison, United States |
Submitting User: | abuchberger |
Hu M, Helfenbein K, Buchberger AR, DeLaney K, Liu Y, Li L.
Exploring the Sexual Dimorphism of Crustacean Neuropeptide Expression Using Callinectes sapidus as a Model Organism.
J Proteome Res. 2021 May 7;20(5):2739-2750. Epub 2021 Apr 19.
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