MassIVE MSV000097297

Complete Public PXD061755

Pathogenesis of focal segmental glomerulosclerosis and minimal change disease

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Description

Podocyte injury is the hallmark of both focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) and is ultimately reflected in foot process effacement proteinuria. Triggers and pathogenic pathways leading to podocyte cytoskeleton rearrangements are however incompletely explained. Here, we aimed to contribute to the understanding of these pathways using tissue bottom-up proteomic profiling of laser capture micro dissected glomeruli from MCD and FSGS. [doi:10.25345/C5251FX92] [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: focal segmental glomerulosclerosis ; minimal change disease ; glomerular disease ; label-free proteomics ; DatasetType:Proteomics

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Principal Investigators:
(in alphabetical order) 		Iuga Cristina-Adela, MEDFUTURE Research Center for Advanced Medicine, Romania
Submitting User: ioanapralea
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Distinct protein accessions are counted across all files submitted in the "Statistical Analysis of Quantified Analytes" category having a "Protein" column in this dataset.

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