Raw DIA/DDA data to support Thesaurus manuscript. The human phosphorylation regulatory network represents a complex signaling cascade where proteins can be phosphorylated at multiple sites resulting in different functional states. Here we present Thesaurus, a hybrid search engine that detects, localizes, and quantifies novel positional isomers using site-specific fragment ions directly from data independent acquisition mass spectrometry experiments. This software works for several PTMs in addition to phosphorylation. Thesaurus is freely available from https://bitbucket.org/searleb/thesaurus
[dataset license: CC0 1.0 Universal (CC0 1.0)]
Keywords: data independent acquisition ; phosphoproteomics ; positional isomers
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Brian Searle, University of Washington, United States Judit Villen, University of Washington, USA |
Submitting User: | searleb |
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Owner | Reanalyses | |
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