MassIVE MSV000083951

Partial Public PXD006557

TAILS N-terminomics of the human dental pulp stroma and the odontoblast layer

Description

We report the targeted analysis of the human dental pulp stroma and the odontoblast layer using the positional proteomics technique TAILS N-terminomics, which allowed us to capture both naturally blocked and unblocked protein N-termini, and to identify differences between e.g. the dental pulp proteomes of older and younger donors. Noteworthy, these differences were most pronounced in the odontoblast region. Note: This study is a follow-up on PXD002264. [dataset license: CC0 1.0 Universal (CC0 1.0)]

Keywords: LC-MSMS ; human ; pulp ; stroma ; odontoblast ; CHPP ; TAILS ; N-terminomics ; positional proteomics

Contact

Principal Investigators: Prof. Christopher Mark Overall, Centre for Blood Research, Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada, N/A
Submitting User: ccms

Publications

Abbey SR, Eckhard U, Solis N, Marino G, Matthew I, Overall CM.
The Human Odontoblast Cell Layer and Dental Pulp Proteomes and N-Terminomes.
J. Dent. Res. 2018 Mar;97(3):338-346. Epub 2017 Oct 16.

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Originally identified proteins that were automatically remapped by MassIVE to proteins in the SwissProt human reference database.
Number of distinct protein accessions reported by originally submitted search results.